Document Details

Document Type : Article In Journal 
Document Title :
Selenium Status and Cardiovascular Risk Profile in Healthy Adult Saudi Males
Selenium Status and Cardiovascular Risk Profile in Healthy Adult Saudi Males
 
Document Language : English 
Abstract : The purpose of this research was to investigate the relationship between selenium levels, thyroid function and other coronary risk factors in 140 Saudi subjects without overt coronary heart disease stratified by age. Demographic data and serum fasting lipid profile, glucose, thyroid function tests, selenium status and dietary intake was assessed. The relationships between selenium status, thyroid function and cardiovascular risk factors were assessed by univariate and multivariate analysis. The results showed that thyroid hormone levels did not differ with age. Erythrocyte glutathione peroxidase (GPx) levels were significantly higher in the youngest vs. oldest tertile (p<0.0001). Selenium and iodine intake did not differ significantly with age tertile, but the average intake for the population sample was below the estimated average requirements for both elements. Serum lipoprotein (a) concentrations correlated with selenium (r = 0.417, p<0.0001) and TSH (r = 0.172, p<0.05). After adjustment for confounding variables; serum fT4 and erythrocytes GPx remained significant determinants of serum TSH levels, whilst serum selenium and TSH were determinants of serum fT4 levels. Serum Lp(a), a coronary risk factor, was strongly related to measures of selenium status. A significant relationship between measures of selenium status and thyroid function was found. Serum Lp(a) a known risk factor for cardiovascular disease was also related to selenium status in our population. 
ISSN : 1658-3175 
Journal Name : Molecules 
Volume : 14 
Issue Number : 1 
Publishing Year : 2009 AH
2009 AD 
Article Type : Article 
Added Date : Monday, March 15, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ايماان العيسىAlissa, Eman ResearcherDoctorate 

Files

File NameTypeDescription
 25979.docx docx 

Back To Researches Page